Based on a suggestion from my dermatologist, I used Sarna for a long term itch in my lower abdominal area. It worked like a miracle lotion for 60 days, after which it began to lose its effectiveness and had to increase the applications from twice a day to 3-4 times a day. It was a hassle but continued to mostly help the symptons. After a 2-3 weeks of the increased dosage I started to notice the roof of my mouth was sore and I was getting a dizzy feeling. I stopped using Sarna and within 24 hours the sore feeling in my mouth was gone and after a few days the dizzy feeling is improving. I give the lotion 4 stars since it worked great and I may use again on a short term basis after I detox for awhile.