I have been using the Stimulastine's and I love them. I recently incorporated the new Cellular Code into my regiment, which promotes the life of the cell. I've been using the Advanced Optimizers for the past 3 years and have noticed a major difference in my skin. However the Optimizer Creme is a bit rich for day-time use, so I recently started switching out the Stimulastine Jour for the Optimizer Creme for day-time use and have noticed a huge difference. The Stimulastin Jour focuses on the elasticity which can be compromised due to dehydration or from using retinol creams without replenishing.